Well, yes and no.
Regarding configuration... this all depends on the wifi specific chipset available in (or for) your MiniPC (either a bundled option, or what will fit into your setup based on the interface type and physical form factor requirements). You want a chipset that is supported by OpenWrt and that has AP mode operation that is reasonably well established (some chipsets do not support, or don't have drivers for AP operation, they work in STA/client mode only, and some wifi hardware isn't supported by OpenWrt at all).
Thermal envelopes will depend on the power dissipation of your wifi chipset/card, and the thermal design of your mini PC (fanless vs active cooling, size/position/CFM rating of the fan(s), plastic enclosure vs metal with large cooling fins, etc.)
Performance, as @vgaetera pointed out, is going to be a personal definition. But, when talking about performance, you have to consider the antenna design, quantity, and position. For high performance wifi APs, the antennas tend to be specifically arranged and then factory calibrated to enable proper multi-stream/multi-user capabilities. Because the positions of the antennas are critical to the wifi performance, this is something that is very carefully designed and controlled by most AP manufacturers, and isn't really possible to achieve in most PC/mini-PC form factors.
More generally, wifi performance depends on your physical environment (including radio frequency noise/spectrum crowding, building materials and floor plan, distance requirements, and the like), and the number of wifi client devices, and the bandwidth requirements.
Of course, your expectations for coverage and bandwidth needs (device-to-device and/or device-to-internet) are what will matter most here, once you actually try it.
So, I agree with @vgaetera that there's no harm in trying it. However, also consider the financial aspect if you'll be paying for the wifi hardware in the mini PC as either a model/option upgrade or an additional purchase... if you're not happy with the internal wifi, you'll likely want to buy an AP.