Sure.
- Powered on the device with stock firmware.
- Selected to update firmware
- Uploaded
openwrt-ramips-mt7621-zyxel_nwa50ax-squashfs-factory.bin
which I found from this thread Porting to ZyXEL NWA50AX - Left the device in an 'Uploading firmware' state until light turned solid green
At that point there was no more AP, ethernet connection, and seemingly serial console.