Unload no, if it's permanent, rmmod them post boot, in rc.local, or create an image without the ath10k packages included, using the online image builder.
Not that much, but if you have more APs and better roaming range w/ 2.4
(FT 802.11r still does not work in 21.+ versions)
with ~12 clients
...
PSE Voltage : 54.5 V PSE Reserved Power : 3.1 W
PD Amperage Draw : 53 mA PD Power Draw : 2.9 W
PSE Voltage : 54.5 V PSE Reserved Power : 3.1 W
PD Amperage Draw : 54 mA PD Power Draw : 3.0 W
...
modprobe ath10k_pci
PSE Voltage : 54.5 V PSE Reserved Power : 4.2 W
PD Amperage Draw : 73 mA PD Power Draw : 4.0 W
uci set wireless.radio0.disabled='0'
uci commit
PSE Voltage : 54.5 V PSE Reserved Power : 4.3 W
PD Amperage Draw : 76 mA PD Power Draw : 4.2 W