I've noticed that saving and applying changes in LuCI doesn't work if I don't restart the firewall service. Some rules don't work either.
This rule does work:
config rule
option name 'AdGuardHome para invitados'
option src 'invitados'
option dest 'lan'
list dest_ip '192.168.1.11'
option dest_port '53'
option target 'ACCEPT'
But not this one:
config rule
option name 'Bloquear servidores DNS externos en invitados'
option src 'invitados'
option dest 'wan'
option dest_port '53 853'
option target 'DROP'