Hi,
it seems I have been able to fix the situation. The prob was not in the config of adblock, but in the config of dnsmasq.
I have configured dnsmasq in "Network/DHCP and DNS/Advanced/Additional servers file" to the file /tmp/dnsmasq.d/adb_list.overall, but according to the manpage of dnsmasq this setting is only a directory with files in it dnsmasq reads. So I changed this setting to /tmp/dnsmasq.d/ and voila, it works:
/etc/init.d/adblock status
::: adblock runtime information
+ adblock_status : enabled
+ adblock_version : 4.0.7
+ blocked_domains : 148807
+ active_sources : adaway adguard android_tracking disconnect firetv_tracking gaming openphish phishing_army reg_cn reg_cz reg_de reg_es reg_fi reg_fr reg_id reg_it reg_kr reg_nl reg_pl1 reg_pl2 reg_ro reg_ru reg_vn smarttv_tracking spam404 stopforumspam wally3k whocares winhelp winspy yoyo
+ dns_backend : dnsmasq, /tmp/dnsmasq.d
+ run_utils : /usr/bin/wget, /usr/bin/gawk
+ run_ifaces : trigger: -, report: br-lan
+ run_directories : base: /tmp, backup: /tmp, report: /tmp, jail: /tmp
+ run_flags : backup: 1, reset: 0, flush: 0, force: 0, search: 0, report: 1, mail: 0, jail: 0
+ last_run : reload, 2m 40s, 253/164/154, 27.10.2021 20:45:25
+ system : OpenWrt 19.07.8 r11364-ef56c85848
Maybe I have changed this setting to a "better one", in my imagination. But not according to the docu of dnsmasq. Maybe the description of the point in the menu of luci is unclear "Additional servers file", and the help text below is also not constructive: "This file may contain lines like.. ". That sounds like you can specify a file but not a directory.
Anyway. It seems to work now. Holy shit. But at least this explains the message in the error log:
Wed Oct 27 13:24:23 2021 user.err adblock-4.0.7[12762]: dns backend restart with adblock blocklist failed
dnsmasq was not able to open a file when it was expecting a directory !
Thanks for your assistance 



